Urinary Tract Infections (UTI) Among Patients at the University Hospital Center "Mother Theresa", Tirana, Albania.

Selam Shkurti

Abstract


Background & objectives: The resistance of bacteria causing urinary tract infection (UTI) to
commonly prescribed antibiotics is increasing both in developing as well as in developed
countries. Resistance has emerged even to more potent antimicrobial agents. The primary
objective of the study was 1) to detect the prevalence rate of bacterial infection among urinary
isolates from patients having UTI and 2)to detect prevalence rate of drug resistance among
pathogen isolate from patients having UTI.
Methods: Early morning mid-stream urine samples were collected using sterile, wide
mouthed container with screw cap tops. On the urine sample bottles were indicated name, age,
sex, and time of collection along with requisition forms.
Results:. Significant association (P<0.001) of prior use of antibiotics in males, UTI in adults,
gynaecological surgery in females, obstructive uropathy in males and complicated UTI in
females with the occurrence of UTI with ciprofloxacin resistant Escherichia coli was noted.
Significant association was noted in females with prior antibiotics, with prior urological
surgery and in males with prior complicated UTI. Fluoroquinolone resistance was found to
increase with age.
Interpretations & conclusions: Ciprofloxacin resistance has emerged due to its frequent use.
This resistance was seen more in the in-patients, elderly males and females. Also the
resistance to other antibiotics was also high. Increasing antibiotic resistance trends indicate
that it is imperative to rationalize the use of antimicrobials in the community and also use
these conservatively.

Key words: Ciprofloxacin - Escherichia coli - minimum inhibitory concentration - urinary tract infection


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ISSN 2385-2712         EISSN 2385-2453