Relation between the Demographic & Clinical Characteristic and the Etiology of Obstructive Jaundice.

Klerida Shehu, Adriana Babameto, Sonela Xinxo, Benard Shehu, Albana Duni, Steka Taci, Luljeta Cakerri

Abstract


Background and Objectives: Early detection of obstructive jaundice etiology can facilitate clinicians on the right and accuracy treatment and consequently will improve quality of life of patient and particularly the survival rates among the patients with malign pathology. Thus the aim of our study is to determine the clinical predictor of the etiology of obstructive jaundice.
Methods: A retrospective study was carried out in Mother Teresa university hospital center during a one year period. Patients’ age and gender, clinical signs were collected including location and duration of pain at the admission, fever and pruritis, dark urination and clay colored stool for the underlying the obstructing pathology. SPSS is used for analysis the data.
Results: Fifty-six patients with obstructive jaundice were included in the study. The malignant pathologies found in 52% of patients. The patients who presented at admission with a history of pain less than 48 h are more likely to have a benign etiology of the obstructive jaundice ( OR =3.9 p<0.05). The presence of colic pain and fever during the episode of the obstructive jaundice is more likely associated with the benign etiology of the obstructive jaundice (OR=3.2; OR =4.3 p<0.05). The patients who did not reported weight loss, dark urination or generalized jaundice during their history of disease are more likely to have a benign etiology (OR 0.28; OR 0.18; OR=0.3 p<0.05).
Interpretation & Conclusion. The demographic characteristics usually do not predict the etiology of the obstructive jaundice. A weight loss, generalized jaundice and dark urination indicate a malign etiology meanwhile presence of fever and colic pain indicates a benign etiology.

Key words: obstructive jaundice, clinical profile, prediction, etiology


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Copyright (c) 2015 Klerida Shehu, Adriana Babameto, Sonela Xinxo, Benard Shehu, Albana Duni, Steka Taci, Luljeta Cakerri

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ISSN 2385-2712         EISSN 2385-2453